comparison parameterStore/MAPparamsPL.m @ 38:c2204b18f4a2 tip

End nov big change
author Ray Meddis <rmeddis@essex.ac.uk>
date Mon, 28 Nov 2011 13:34:28 +0000
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37:771a643d5c29 38:c2204b18f4a2
1 function method=MAPparamsPL ...
2 (BFlist, sampleRate, showParams, paramChanges)
3 % MAPparamsPL.m is a parameter file, similar in all respects to
4 % MAPparamsNormal except that a primary-like' neuron is used at the
5 % level of the cochlear nuclues (rather than a chopper cell).
6 %
7 % MAPparams<> establishes a complete set of MAP parameters
8 % Parameter file names must be of the form <MAPparams><name>
9 %
10 % Input arguments
11 % BFlist (optional) specifies the desired list of channel BFs
12 % otherwise defaults set below
13 % sampleRate (optional), default is 50000.
14 % showParams (optional) =1 prints out the complete set of parameters
15 % Output argument
16 % method passes a miscelleny of values
17 % the use of 'method' is being phased out. use globals
18
19 global inputStimulusParams OMEParams DRNLParams IHC_cilia_RPParams
20 global IHCpreSynapseParams AN_IHCsynapseParams
21 global MacGregorParams MacGregorMultiParams filteredSACFParams
22 global experiment % used only by calls from multiThreshold
23 % global IHC_VResp_VivoParams
24
25 currentFile=mfilename; % i.e. the name of this mfile
26 method.parameterSource=currentFile(10:end); % for the record
27
28 efferentDelay=0.010;
29 method.segmentDuration=efferentDelay;
30
31 if nargin<3, showParams=0; end
32 if nargin<2, sampleRate=50000; end
33 if nargin<1 || BFlist(1)<0 % if BFlist= -1, set BFlist to default
34 lowestBF=250; highestBF= 8000; numChannels=21;
35 % 21 chs (250-8k)includes BFs at 250 500 1000 2000 4000 8000
36 BFlist=round(logspace(log10(lowestBF),log10(highestBF),numChannels));
37 end
38 % BFlist=1000; % single channel option
39
40 % preserve for backward campatibility
41 method.nonlinCF=BFlist;
42 method.dt=1/sampleRate;
43
44 %%%%%%%%%%%%%%%%%%%%%%%%%%%%
45 % set model parameters
46 %%%%%%%%%%%%%%%%%%%%%%%%%%%%
47
48 %% #1 inputStimulus
49 inputStimulusParams=[];
50 inputStimulusParams.sampleRate= sampleRate;
51
52 %% #2 outerMiddleEar
53 OMEParams=[]; % clear the structure first
54 % outer ear resonances band pass filter [gain lp order hp]
55 OMEParams.externalResonanceFilters= [ 10 1 1000 4000];
56
57 % highpass stapes filter
58 % Huber gives 2e-9 m at 80 dB and 1 kHz (2e-13 at 0 dB SPL)
59 OMEParams.OMEstapesHPcutoff= 1000;
60 OMEParams.stapesScalar= 45e-9;
61
62 % Acoustic reflex: maximum attenuation should be around 25 dB (Price, 1966)
63 % i.e. a minimum ratio of 0.056.
64 % 'spikes' model: AR based on brainstem spiking activity (LSR)
65 OMEParams.rateToAttenuationFactor=0.05; % * N(all ICspikes)
66 % 'probability model': Ar based on AN firing probabilities (LSR)
67 OMEParams.rateToAttenuationFactorProb=0.02; % * N(all ANrates)
68
69 % asymptote should be around 100-200 ms
70 OMEParams.ARtau=.250; % AR smoothing function 250 ms fits Hung and Dallos
71 % delay must be longer than the segment length
72 OMEParams.ARdelay=efferentDelay; %Moss gives 8.5 ms latency
73 OMEParams.ARrateThreshold=40;
74
75 %% #3 DRNL
76 DRNLParams=[]; % clear the structure first
77 % DRNLParams.BFlist=BFlist;
78
79 % *** DRNL nonlinear path
80 % broken stick compression
81 DRNLParams.a=2e4; % DRNL.a=0 means no OHCs (no nonlinear path)
82 DRNLParams.c=.2; % compression exponent
83 DRNLParams.ctBMdB = 10; %Compression threshold dB re 10e-9 m displacement
84
85 % filters
86 DRNLParams.nonlinOrder= 3; % order of nonlinear gammatone filters
87 DRNLParams.nonlinCFs=BFlist;
88 DRNLParams.p=0.2895; DRNLParams.q=250; % save p and q for printing only
89 % p=0.2895; q=250; % human (% p=0.14; q=366; % cat)
90 DRNLParams.nlBWs= DRNLParams.p * BFlist + DRNLParams.q;
91
92 % *** DRNL linear path:
93 DRNLParams.g=100; % linear path gain factor
94 DRNLParams.linOrder=3; % order of linear gammatone filters
95 % linCF is not necessarily the same as nonlinCF
96 minLinCF=153.13; coeffLinCF=0.7341; % linCF>nonlinBF for BF < 1 kHz
97 DRNLParams.linCFs=minLinCF+coeffLinCF*BFlist;
98 % bandwidths (linear)
99 minLinBW=100; coeffLinBW=0.6531;
100 DRNLParams.linBWs=minLinBW + coeffLinBW*BFlist; % bandwidths of linear filters
101
102 % *** DRNL MOC efferents
103 DRNLParams.MOCdelay = efferentDelay; % must be < segment length!
104 DRNLParams.minMOCattenuationdB=-35;
105
106 % 'spikes' model: MOC based on brainstem spiking activity (HSR)
107 DRNLParams.MOCtau =.0285; % smoothing for MOC
108 DRNLParams.rateToAttenuationFactor = .03; % strength of MOC
109 DRNLParams.rateToAttenuationFactor = .0055; % strength of MOC
110
111 % 'probability' model: MOC based on AN probability (HSR)
112 DRNLParams.MOCtauProb =.285; % smoothing for MOC
113 DRNLParams.rateToAttenuationFactorProb = 0.007; % strength of MOC
114 DRNLParams.MOCrateThresholdProb =67; % spikes/s probability only
115
116
117 %% #4 IHC_cilia_RPParams
118 IHC_cilia_RPParams.tc= 0.00012; % 0.0003 Shamma
119 IHC_cilia_RPParams.C= 0.08; % 0.1 scalar (C_cilia )
120 IHC_cilia_RPParams.u0= 5e-9;
121 IHC_cilia_RPParams.s0= 30e-9;
122 IHC_cilia_RPParams.u1= 1e-9;
123 IHC_cilia_RPParams.s1= 1e-9;
124
125 IHC_cilia_RPParams.Gmax= 6e-9; % 2.5e-9 maximum conductance (Siemens)
126 IHC_cilia_RPParams.Ga= 1e-9; % 4.3e-9 fixed apical membrane conductance
127 IHC_cilia_RPParams.Ga= .8e-9; % 4.3e-9 fixed apical membrane conductance
128
129 % #5 IHC_RP
130 IHC_cilia_RPParams.Cab= 4e-012; % IHC capacitance (F)
131 % IHC_cilia_RPParams.Cab= 1e-012; % IHC capacitance (F)
132 IHC_cilia_RPParams.Et= 0.100; % endocochlear potential (V)
133
134 IHC_cilia_RPParams.Gk= 2e-008; % 1e-8 potassium conductance (S)
135 IHC_cilia_RPParams.Ek= -0.08; % -0.084 K equilibrium potential
136 IHC_cilia_RPParams.Rpc= 0.04; % combined resistances
137
138
139 %% #5 IHCpreSynapse
140 IHCpreSynapseParams=[];
141 IHCpreSynapseParams.GmaxCa= 14e-9;% maximum calcium conductance
142 % IHCpreSynapseParams.GmaxCa= 12e-9;% maximum calcium conductance
143 IHCpreSynapseParams.ECa= 0.066; % calcium equilibrium potential
144 IHCpreSynapseParams.beta= 400; % determine Ca channel opening
145 IHCpreSynapseParams.gamma= 100; % determine Ca channel opening
146 IHCpreSynapseParams.tauM= 0.00005; % membrane time constant ?0.1ms
147 IHCpreSynapseParams.power= 3;
148 % reminder: changing z has a strong effect on HF thresholds (like Et)
149 IHCpreSynapseParams.z= 2e42; % scalar Ca -> vesicle release rate
150
151 LSRtauCa=30e-6; HSRtauCa=80e-6; % seconds
152 % LSRtauCa=40e-6; HSRtauCa=90e-6; % seconds
153 % IHCpreSynapseParams.tauCa= [15e-6 80e-6]; %LSR and HSR fiber
154 IHCpreSynapseParams.tauCa= [LSRtauCa HSRtauCa]; %LSR and HSR fiber
155
156 %% #6 AN_IHCsynapse
157 AN_IHCsynapseParams=[]; % clear the structure first
158 % number of AN fibers at each BF (used only for spike generation)
159 AN_IHCsynapseParams.numFibers= 100;
160 % absolute refractory period. Relative refractory period is the same.
161 AN_IHCsynapseParams.refractory_period= 0.00075;
162 AN_IHCsynapseParams.TWdelay=0.004; % ?delay before stimulus first spike
163 AN_IHCsynapseParams.spikesTargetSampleRate=sampleRate;
164 % AN_IHCsynapseParams.ANspeedUpFactor=5; % longer epochs for computing spikes.
165
166 % c=kym/(y(l+r)+kl) (spontaneous rate)
167 % c=(approx) ym/l (saturated rate)
168 AN_IHCsynapseParams.M= 12; % maximum vesicles at synapse
169 AN_IHCsynapseParams.y= 4; % depleted vesicle replacement rate
170 AN_IHCsynapseParams.y= 6; % depleted vesicle replacement rate
171
172 AN_IHCsynapseParams.x= 30; % replenishment from re-uptake store
173 AN_IHCsynapseParams.x= 60; % replenishment from re-uptake store
174
175 % reduce l to increase saturated rate
176 AN_IHCsynapseParams.l= 100; % *loss rate of vesicles from the cleft
177 AN_IHCsynapseParams.l= 250; % *loss rate of vesicles from the cleft
178
179 AN_IHCsynapseParams.r= 500; % *reuptake rate from cleft into cell
180 % AN_IHCsynapseParams.r= 300; % *reuptake rate from cleft into cell
181
182
183 %% #7 MacGregorMulti (first order brainstem neurons)
184 MacGregorMultiParams=[];
185 % MacGregorMultiType='chopper'; % MacGregorMultiType='primary-like'; %choose
186 MacGregorMultiType='primary-like'; % MacGregorMultiType='primary-like'; %choose
187 switch MacGregorMultiType
188 case 'primary-like'
189 MacGregorMultiParams.nNeuronsPerBF= 10; % N neurons per BF
190 MacGregorMultiParams.type = 'primary-like cell';
191 MacGregorMultiParams.fibersPerNeuron=4; % N input fibers
192 MacGregorMultiParams.dendriteLPfreq=500; % dendritic filter
193 MacGregorMultiParams.currentPerSpike=0.11e-6; % (A) per spike
194 MacGregorMultiParams.Cap=4.55e-9; % cell capacitance (Siemens)
195 MacGregorMultiParams.tauM=5e-4; % membrane time constant (s)
196 MacGregorMultiParams.Ek=-0.01; % K+ eq. potential (V)
197 MacGregorMultiParams.dGkSpike=3.64e-5; % K+ cond.shift on spike,S
198 MacGregorMultiParams.tauGk= 0.0005; % K+ conductance tau (s)
199 MacGregorMultiParams.Th0= 0.01; % equilibrium threshold (V)
200 MacGregorMultiParams.c= 0.01; % threshold shift on spike, (V)
201 MacGregorMultiParams.tauTh= 0.015; % variable threshold tau
202 MacGregorMultiParams.Er=-0.06; % resting potential (V)
203 MacGregorMultiParams.Eb=0.06; % spike height (V)
204
205 case 'chopper'
206 MacGregorMultiParams.nNeuronsPerBF= 10; % N neurons per BF
207 MacGregorMultiParams.type = 'chopper cell';
208 MacGregorMultiParams.fibersPerNeuron=10; % N input fibers
209
210 MacGregorMultiParams.dendriteLPfreq=50; % dendritic filter
211 MacGregorMultiParams.currentPerSpike=28e-9; % *per spike
212 % MacGregorMultiParams.currentPerSpike=30e-9; % *per spike
213
214 MacGregorMultiParams.Cap=1.67e-8; % ??cell capacitance (Siemens)
215 MacGregorMultiParams.tauM=0.002; % membrane time constant (s)
216 MacGregorMultiParams.Ek=-0.01; % K+ eq. potential (V)
217 MacGregorMultiParams.dGkSpike=1.33e-4; % K+ cond.shift on spike,S
218 MacGregorMultiParams.tauGk= 0.0005;% K+ conductance tau (s)
219 MacGregorMultiParams.Th0= 0.01; % equilibrium threshold (V)
220 MacGregorMultiParams.c= 0; % threshold shift on spike, (V)
221 MacGregorMultiParams.tauTh= 0.02; % variable threshold tau
222 MacGregorMultiParams.Er=-0.06; % resting potential (V)
223 MacGregorMultiParams.Eb=0.06; % spike height (V)
224 MacGregorMultiParams.PSTHbinWidth= 1e-4;
225 end
226
227 %% #8 MacGregor (second-order neuron). Only one per channel
228 MacGregorParams=[]; % clear the structure first
229 MacGregorParams.type = 'chopper cell';
230 MacGregorParams.fibersPerNeuron=10; % N input fibers
231 MacGregorParams.dendriteLPfreq=100; % dendritic filter
232 MacGregorParams.currentPerSpike=40e-9;% *(A) per spike
233
234 MacGregorParams.Cap=16.7e-9; % cell capacitance (Siemens)
235 MacGregorParams.tauM=0.002; % membrane time constant (s)
236 MacGregorParams.Ek=-0.01; % K+ eq. potential (V)
237 MacGregorParams.dGkSpike=1.33e-4; % K+ cond.shift on spike,S
238 MacGregorParams.tauGk= 0.0012; % K+ conductance tau (s)
239 MacGregorParams.Th0= 0.01; % equilibrium threshold (V)
240 MacGregorParams.c= 0; % threshold shift on spike, (V)
241 MacGregorParams.tauTh= 0.02; % variable threshold tau
242 MacGregorParams.Er=-0.06; % resting potential (V)
243 MacGregorParams.Eb=0.06; % spike height (V)
244 MacGregorParams.debugging=0; % (special)
245 % wideband accepts input from all channels (of same fiber type)
246 % use wideband to create inhibitory units
247 MacGregorParams.wideband=0; % special for wideband units
248 % MacGregorParams.saveAllData=0;
249
250 %% #9 filteredSACF
251 minPitch= 300; maxPitch= 3000; numPitches=60; % specify lags
252 pitches=100*log10(logspace(minPitch/100, maxPitch/100, numPitches));
253 filteredSACFParams.lags=1./pitches; % autocorrelation lags vector
254 filteredSACFParams.acfTau= .003; % time constant of running ACF
255 filteredSACFParams.lambda= 0.12; % slower filter to smooth ACF
256 filteredSACFParams.plotFilteredSACF=1; % 0 plots unfiltered ACFs
257 filteredSACFParams.plotACFs=0; % special plot (see code)
258 % filteredSACFParams.usePressnitzer=0; % attenuates ACF at long lags
259 filteredSACFParams.lagsProcedure= 'useAllLags';
260 % filteredSACFParams.lagsProcedure= 'omitShortLags';
261 filteredSACFParams.criterionForOmittingLags=3;
262
263 % checks
264 if AN_IHCsynapseParams.numFibers<MacGregorMultiParams.fibersPerNeuron
265 error('MacGregorMulti: too few input fibers for input to MacG unit')
266 end
267
268
269 %% now accept last minute parameter changes required by the calling program
270 % paramChanges
271 if nargin>3 && ~isempty(paramChanges)
272 if ~iscellstr(paramChanges)
273 error('paramChanges error: paramChanges not a cell array')
274 end
275
276 nChanges=length(paramChanges);
277 for idx=1:nChanges
278 x=paramChanges{idx};
279 x=deblank(x);
280 if ~isempty(x)
281 if ~strcmp(x(end),';')
282 error(['paramChanges error (terminate with semicolon) ' x])
283 end
284 st=strtrim(x(1:strfind(x,'.')-1));
285 fld=strtrim(x(strfind(x,'.')+1:strfind(x,'=')-1));
286 value=x(strfind(x,'=')+1:end);
287 if isempty(st) || isempty(fld) || isempty(value)
288 error(['paramChanges error:' x])
289 end
290
291 x1=eval(['isstruct(' st ')']);
292 cmd=['isfield(' st ',''' fld ''')'];
293 x2=eval(cmd);
294 if ~(x1*x2)
295 error(['paramChanges error:' x])
296 end
297 end
298
299 % no problems so go ahead
300 eval(paramChanges{idx})
301 end
302 end
303
304
305 %% write all parameters to the command window
306 % showParams is currently set at the top of htis function
307 if showParams
308 fprintf('\n %%%%%%%%\n')
309 fprintf('\n%s\n', method.parameterSource)
310 fprintf('\n')
311 nm=UTIL_paramsList(whos);
312 for i=1:length(nm)
313 % eval(['UTIL_showStruct(' nm{i} ', ''' nm{i} ''')'])
314 if ~strcmp(nm(i), 'method')
315 eval(['UTIL_showStructureSummary(' nm{i} ', ''' nm{i} ''', 10)'])
316 end
317 end
318
319 % highlight parameter changes made locally
320 if nargin>3 && ~isempty(paramChanges)
321 fprintf('\n Local parameter changes:\n')
322 for i=1:length(paramChanges)
323 disp(paramChanges{i})
324 end
325 end
326 end
327
328 % for backward compatibility
329 experiment.comparisonData=[];